Premium Rubber: Many pet tennis balls are made of high - quality rubber material. It is non - toxic, odorless, safe and reliable, with strong bite resistance. It can withstand the powerful bites of pets. Even large dogs like Golden Retrievers can hardly damage it easily. Moreover, the rubber material can also ensure a certain elasticity, attracting pets to chase and pounce. There are also those made of natural rubber combined with plush material, which are not only bite - resistant but also can make sounds to stimulate pets' interest.